Faculty of Art and Science

Academic Members

Aslı Kutlu

Aslı Kutlu,  Dr.

CV
Öğretim Görevlisi

Aslı Kutlu completed her undergraduate studies in 2012 at the department of Chemical and Biological Engineering at Koç University. In 2012, she started her PhD at the department of Molecular Biology, Genetics and Bioengineering. Sabancı University, under the supervision of Prof. Uğur Sezerman. Her research studies are about the protein engineering application of cellulase and lipase enzymes from the perspective of both experimental and computation point of view. After receiving PhD at 2017, she works as post-doctoral fellow at Acıbadem Mehmet Aydınlar University, Department of Medical Statistics and Bioinformatics, School of Medicine, where she again joined to Sezerman Lab. During the post-doctoral fellowship, she mostly focused on the investigation of rare disease mechanism through molecular dynamics (MD) studies to elucidate the roles of novel mutations. In 2019 February, she started to work at Biruni University as Assistant Professor. Now, she has joined to İstinye University, the department of molecular biology and genetics. Still, her research studies are about the investigation of rare disease mechanism through MD studies and the identification of novel genes as potential biomarkers for Head-and-Neck cancer and Cholangiocarcinoma. Aslı Kutlu is the author of 6 articles and she is a principle investigator of TUBITAK-1002 project and a researcher in several BAP-projects.

Research Area: Biyoinformatik, Protein Engineering, Protein Biochemistry, Bioinformatics Analysis, Medical genetics, Molecular Genetics, Modeling and Simulation

Main Areas: Biyomedikal Mühendisliği,  Biyoenformatik,  Biyoteknoloji, 

2020 - Elucidating the roles of naturally occurring silent mutations in Polycystic Ovary Syndrome (PCOS)
Gümüşgül Meryem Dilara,Şahin Şuara,Turan Hatice Kübra,TAKTAK KARACA BANU,YENENLER ASLI. Meta Gene,
2020 - Understanding the impacts of self-shuffling approach on structure and function of shuffled endoglucanase enzyme via MD simulations
YENENLER ASLI,Gerlevik Umut,sezerman osman uğur. Turkish Journal of Biochemistry, 45(2),
2019 - A possible founder mutation in FZD6 gene in a Turkish family with autosomal recessive nail dysplasia
Saygı Ceren,ALANAY YASEMİN,SEZERMAN OSMAN UĞUR,YENENLER ASLI,ÖZÖREN NESRİN. BMC Medical Genetics, 20(1),
2019 - Enhancing Enzymatic Properties of Endoglucanase I Enzyme from Trichoderma Reesei via Swapping from Cellobiohydrolase I Enzyme
YENENLER ASLI,KURT HASAN,sezerman osman uğur. CATALYSTS, 9(2),
2018 - Investigating the structural properties of the active conformation BTL2 of a lipase from Geobacillus thermocatenulatus in toluene using molecular dynamic simulations and engineering BTL2 via in-silico mutation
YENENLER ASLI,sezerman osman uğur. JOURNAL OF MOLECULAR MODELING, 24(9),
2016 - Desing and characterization of two novel cellulases through single gene shuffling of Cel12A (EG3) gene from Trichoderma reesei
YENENLER ASLI,sezerman osman uğur. PROTEIN ENGINEERING DESIGN SELECTION, 29(6), 219-229.